ZBP-89 reduces the cell death threshold in hepatocellular carcinoma cells by increasing caspase-6 and S phase cell-cycle arrest

ZBP-89 inhibits the some tumor cells but its role in HCC is unknown. We investigated effect of ZBP-89 on cell death of 5 HCC cell lines with different status of p53. We found that ZBP-89 significantly induced cell death of all HCC cells particularly those with wild-type p53. The inhibition was well...

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Hauptverfasser: Chen, George G, Chan, Ursula PF, Bai, Long-Chuan, Fung, King Yip, Tessier, Art, To, Ann KY, Merchant, Juanita L, Lai, Paul BS
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104054/
https://ncbi.nlm.nih.gov/pubmed/19362768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.03.024
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