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Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma

ZBP-89, a zinc finger transcription factor, participates in histone deacetylases inhibitors (HDACi)-mediated growth arrest and apoptosis in cancer cells. p53 mutants may interact with ZBP-89 that transcriptionally regulates p21(Waf1) (p21). However, this interaction and its consequence in cancer tre...

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Détails bibliographiques
Auteurs principaux: Zhang, Chris ZY, Chen, George G, Merchant, Juanita L, Lai, Paul BS
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293381/
https://ncbi.nlm.nih.gov/pubmed/22214764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18758
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