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Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma

ZBP-89 regulates Bak to facilitate apoptosis in cancer cells. This study examined if ZBP-89 regulates Bak through an epigenetic mechanism in hepatocellular carcinoma (HCC). We first demonstrated that the expression of Bak was reduced but the levels of DNMT1 and HDAC3 were increased in HCC cancer tis...

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Bibliografiska uppgifter
Huvudupphovsmän: Ye, Cai Guo, Chen, George G, Ho, Rocky LK, Merchant, Juanita L, He, Ming-Liang, Lai, Paul BS
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160027/
https://ncbi.nlm.nih.gov/pubmed/23954442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.08.001
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