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Markov Models of Amino Acid Substitution to Study Proteins with Intrinsically Disordered Regions

BACKGROUND: Intrinsically disordered proteins (IDPs) or proteins with disordered regions (IDRs) do not have a well-defined tertiary structure, but perform a multitude of functions, often relying on their native disorder to achieve the binding flexibility through changing to alternative conformations...

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Hlavní autoři: Szalkowski, Adam M., Anisimova, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103576/
https://ncbi.nlm.nih.gov/pubmed/21647374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020488
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