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Markov Models of Amino Acid Substitution to Study Proteins with Intrinsically Disordered Regions
BACKGROUND: Intrinsically disordered proteins (IDPs) or proteins with disordered regions (IDRs) do not have a well-defined tertiary structure, but perform a multitude of functions, often relying on their native disorder to achieve the binding flexibility through changing to alternative conformations...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103576/ https://ncbi.nlm.nih.gov/pubmed/21647374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020488 |
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