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Antibody-Specific Model of Amino Acid Substitution for Immunological Inferences from Alignments of Antibody Sequences

Antibodies are glycoproteins produced by the immune system as a dynamically adaptive line of defense against invading pathogens. Very elegant and specific mutational mechanisms allow B lymphocytes to produce a large and diversified repertoire of antibodies, which is modified and enhanced throughout...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Mirsky, Alexander, Kazandjian, Linda, Anisimova, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327158/
https://ncbi.nlm.nih.gov/pubmed/25534034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu340
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