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A Novel Current Pathway Parallel to the Central Pore in a Mutant Voltage-gated Potassium Channel

Voltage-gated potassium channels are proteins composed of four subunits consisting of six membrane-spanning segments S1–S6, with S4 as the voltage sensor. The region between S5 and S6 forms the potassium-selective ion-conducting central α-pore. Recent studies showed that mutations in the voltage sen...

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Autori principali: Prütting, Sylvia, Grissmer, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103376/
https://ncbi.nlm.nih.gov/pubmed/21498510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185405
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