Characterizing the N- and C-terminal Small Ubiquitin-like Modifier (SUMO)-interacting Motifs of the Scaffold Protein DAXX

DAXX is a scaffold protein with diverse roles that often depend upon binding SUMO via its N- and/or C-terminal SUMO-interacting motifs (SIM-N and SIM-C). Using NMR spectroscopy, we characterized the in vitro binding properties of peptide models of SIM-N and SIM-C to SUMO-1 and SUMO-2. In each case,...

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Detalhes bibliográficos
Main Authors: Escobar-Cabrera, Eric, Okon, Mark, Lau, Desmond K. W., Dart, Christopher F., Bonvin, Alexandre M. J. J., McIntosh, Lawrence P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103359/
https://ncbi.nlm.nih.gov/pubmed/21383010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231647
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