Mammalian Polo-like Kinase 1-dependent Regulation of the PBIP1-CENP-Q Complex at Kinetochores

Mammalian polo-like kinase 1 (Plk1) plays a pivotal role during M-phase progression. Plk1 localizes to specific subcellular structures through the targeting activity of the C-terminal polo-box domain (PBD). Disruption of the PBD function results in improper bipolar spindle formation, chromosome miss...

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Autores principales: Kang, Young H., Park, Chi Hoon, Kim, Tae-Sung, Soung, Nak-Kyun, Bang, Jeong K., Kim, Bo Y., Park, Jung-Eun, Lee, Kyung S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103353/
https://ncbi.nlm.nih.gov/pubmed/21454580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224105
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