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Asparagine 175 of Connexin32 Is a Critical Residue for Docking and Forming Functional Heterotypic Gap Junction Channels with Connexin26

The gap junction channel is formed by proper docking of two hemichannels. Depending on the connexin(s) in the hemichannels, homotypic and heterotypic gap junction channels can be formed. Previous studies suggest that the extracellular loop 2 (E2) is an important molecular domain for heterotypic comp...

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Detalhes bibliográficos
Main Authors: Nakagawa, So, Gong, Xiang-Qun, Maeda, Shoji, Dong, Yuhua, Misumi, Yuko, Tsukihara, Tomitake, Bai, Donglin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103346/
https://ncbi.nlm.nih.gov/pubmed/21478159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204958
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