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Aspartic Acid Residue D3 Critically Determines Cx50 Gap Junction Channel Transjunctional Voltage-Dependent Gating and Unitary Conductance

Previous studies have suggested that the aspartic acid residue (D) at the third position is critical in determining the voltage polarity of fast V(j)-gating of Cx50 channels. To test whether another negatively charged residue (a glutamic acid residue, E) could fulfill the role of the D3 residue, we...

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Bibliografske podrobnosti
Main Authors: Xin, Li, Nakagawa, So, Tsukihara, Tomitake, Bai, Donglin
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296025/
https://ncbi.nlm.nih.gov/pubmed/22404924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.008
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