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Charge at the 46th residue of connexin 50 is crucial for the gap-junctional unitary conductance and transjunctional voltage-dependent gating
Gap-junction (GJ) channels are twice the length of most membrane channels, yet they often have large unitary channel conductance (γ(j)). What factors make this possibly the longest channel so efficient in passing ions are not fully clear. Here we studied the lens connexin (Cx) 50 GJs, which display...
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| Udgivet i: | J Physiol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262333/ https://ncbi.nlm.nih.gov/pubmed/25260631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.280636 |
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