Structural and Functional Characterization of Rv2966c Protein Reveals an RsmD-like Methyltransferase from Mycobacterium tuberculosis and the Role of Its N-terminal Domain in Target Recognition

Nine of ten methylated nucleotides of Escherichia coli 16 S rRNA are conserved in Mycobacterium tuberculosis. All the 10 different methyltransferases are known in E. coli, whereas only TlyA and GidB have been identified in mycobacteria. Here we have identified Rv2966c of M. tuberculosis as an orthol...

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Hauptverfasser: Kumar, Atul, Saigal, Kashyap, Malhotra, Ketan, Sinha, Krishna Murari, Taneja, Bhupesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103344/
https://ncbi.nlm.nih.gov/pubmed/21474448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200428
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