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Structural and Functional Characterization of Rv2966c Protein Reveals an RsmD-like Methyltransferase from Mycobacterium tuberculosis and the Role of Its N-terminal Domain in Target Recognition

Nine of ten methylated nucleotides of Escherichia coli 16 S rRNA are conserved in Mycobacterium tuberculosis. All the 10 different methyltransferases are known in E. coli, whereas only TlyA and GidB have been identified in mycobacteria. Here we have identified Rv2966c of M. tuberculosis as an orthol...

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Main Authors: Kumar, Atul, Saigal, Kashyap, Malhotra, Ketan, Sinha, Krishna Murari, Taneja, Bhupesh
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103344/
https://ncbi.nlm.nih.gov/pubmed/21474448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200428
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