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Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis

[Image: see text] Natural product gene clusters are often tightly regulated, resulting in gene cluster silencing in laboratory fermentation studies. The systematic overexpression of transcription factors (TFs) associated with biosynthetic gene clusters found in the genome of Burkholderia thailandens...

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Main Authors: Biggins, John B., Gleber, Conrad D., Brady, Sean F.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103185/
https://ncbi.nlm.nih.gov/pubmed/21348454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200225v
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