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Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis

While bacterial genomes typically contain numerous secondary metabolite biosynthetic gene clusters, only a small fraction of these are expressed at any given time. The remaining majority is inactive or silent, and methods that awaken them would greatly expand our repertoire of bioactive molecules. W...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Autores principales: Okada, Bethany K., Wu, Yihan, Mao, Dainan, Bushin, Leah B., Seyedsayamdost, Mohammad R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786267/
https://ncbi.nlm.nih.gov/pubmed/27367535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00447
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