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Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis

While bacterial genomes typically contain numerous secondary metabolite biosynthetic gene clusters, only a small fraction of these are expressed at any given time. The remaining majority is inactive or silent, and methods that awaken them would greatly expand our repertoire of bioactive molecules. W...

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Bibliografische gegevens
Gepubliceerd in:ACS Chem Biol
Hoofdauteurs: Okada, Bethany K., Wu, Yihan, Mao, Dainan, Bushin, Leah B., Seyedsayamdost, Mohammad R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786267/
https://ncbi.nlm.nih.gov/pubmed/27367535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00447
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