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Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis

Low doses of antibiotics can trigger secondary metabolite biosynthesis in bacteria, but the underlying mechanisms are generally unknown. We sought to better understand this phenomenon by studying how the antibiotic trimethoprim activates the synthesis of the virulence factor malleilactone in Burkhol...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Li, Anran, Mao, Dainan, Yoshimura, Aya, Rosen, Paul C., Martin, W. Lance, Gallant, Étienne, Wühr, Martin, Seyedsayamdost, Mohammad R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042699/
https://ncbi.nlm.nih.gov/pubmed/32098820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03210-19
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