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Salinosporamide Natural Products: Potent 20S Proteasome Inhibitors as Promising Cancer Chemotherapeutics

[Image: see text] Proteasome inhibitors are rapidly evolving as potent treatment options in cancer therapy. One of the most promising drug candidates of this type is salinosporamide A from the bacterium Salinispora tropica. This marine natural product possesses a complex, densely functionalized γ-la...

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Bibliografiske detaljer
Main Authors: Gulder, Tobias A. M., Moore, Bradley S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103133/
https://ncbi.nlm.nih.gov/pubmed/20927786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201000728
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