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The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication

Coxiella burnetii, the causative agent of human Q fever, is an intracellular pathogen that replicates in an acidified vacuole derived from the host lysosomal network. This pathogen encodes a Dot/Icm type IV secretion system that delivers bacterial proteins called effectors to the host cytosol. To id...

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Autors principals: Carey, Kimberly L., Newton, Hayley J., Lührmann, Anja, Roy, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102713/
https://ncbi.nlm.nih.gov/pubmed/21637816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002056
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