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The emerging role of APC/C(Cdh1) in controlling differentiation, genomic stability and tumor suppression
Deregulation of the G1/G0 phase of the cell cycle can lead to cancer. During G1, most cells commit alternatively to DNA replication and division, or to cell cycle exit and differentiation. The anaphase-promoting complex or cyclosome (APC/C) activated by Cdh1 coordinately eliminates positive cell cyc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102600/ https://ncbi.nlm.nih.gov/pubmed/19826416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.325 |
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