IFN Regulatory Factors 4 and 8 Expression in the NOD Mouse

Dendritic cells (DCs) contribute to islet inflammation and its progression to diabetes in NOD mouse model and human. DCs play a crucial role in the presentation of autoantigen and activation of diabetogenic T cells, and IRF4 and IRF8 are crucial genes involved in the development of DCs. We have ther...

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Main Authors: Besin, Gilles, Gaudreau, Simon, Dumont-Blanchette, Émilie, Ménard, Michael, Guindi, Chantal, Dupuis, Gilles, Amrani, Abdelaziz
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102445/
https://ncbi.nlm.nih.gov/pubmed/21647406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/374859
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