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Homologous and non-homologous recombination differentially affect DNA damage repair in mice

Ionizing radiation and interstrand DNA crosslinking compounds provide important treatments against cancer due to their extreme genotoxicity for proliferating cells. Both the efficacies of such treatments and the mutagenic potential of these agents are modulated by the ability of cells to repair the...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Essers, Jeroen, van Steeg, Harry, de Wit, Jan, Swagemakers, Sigrid M.A., Vermeij, Marcel, Hoeijmakers, Jan H.J., Kanaar, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10747037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.7.1703
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