Differential Contributions of Mammalian Rad54 Paralogs to Recombination, DNA Damage Repair, and Meiosis

Homologous recombination is a versatile DNA damage repair pathway requiring Rad51 and Rad54. Here we show that a mammalian Rad54 paralog, Rad54B, displays physical and functional interactions with Rad51 and DNA that are similar to those of Rad54. While ablation of Rad54 in mouse embryonic stem (ES)...

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Detalhes bibliográficos
Main Authors: Wesoly, Joanna, Agarwal, Sheba, Sigurdsson, Stefan, Bussen, Wendy, Van Komen, Stephen, Qin, Jian, van Steeg, Harry, van Benthem, Jan, Wassenaar, Evelyne, Baarends, Willy M., Ghazvini, Mehrnaz, Tafel, Agnieszka A., Heath, Helen, Galjart, Niels, Essers, Jeroen, Grootegoed, J. Anton, Arnheim, Norman, Bezzubova, Olga, Buerstedde, Jean-Marie, Sung, Patrick, Kanaar, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347043/
https://ncbi.nlm.nih.gov/pubmed/16428451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.976-989.2006
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