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Functional relevance of the histone γH2Ax in the response to DNA damaging agents

The phosphorylation of H2Ax on its S139 site, γH2Ax, is important during DNA double-strand repair and is considered necessary for assembly of repair complexes, but its functional role after other kinds of DNA damage is less clear. We have measured the survival of isogenic mouse cell lines with the H...

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Autors principals: Revet, Ingrid, Feeney, Luzviminda, Bruguera, Stephanie, Wilson, Wade, Dong, Tiffany K., Oh, Dennis H., Dankort, David, Cleaver, James E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102364/
https://ncbi.nlm.nih.gov/pubmed/21555580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105866108
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