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Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D

Cardiac myocytes are known to be influenced by the rigidity and topography of their physical microenvironment. It was hypothesized that 3D heterogeneity introduced by purely physical microdomains regulates cardiac myocyte size and contraction. This was tested in vitro using polymeric microstructures...

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Bibliografiske detaljer
Main Authors: Curtis, Matthew W., Sharma, Sadhana, Desai, Tejal A., Russell, Brenda
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102262/
https://ncbi.nlm.nih.gov/pubmed/20668947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-010-9461-y
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