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Stimulus interval, rate and direction differentially regulate phosphorylation for mechanotransduction in neonatal cardiac myocytes

The effect of interval, direction and rate of strain on mechanotransduction in neonatal rat cardiomyocytes is determined for focal adhesion kinase (Y397pFAK), extracellular signal-regulated kinase ERK1/2 (Thr183/Tyr185) and paxillin (pY31) and phosphorylation time courses to 10% strain assessed. Cel...

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Detalhes bibliográficos
Main Authors: Senyo, Samuel E., Koshman, Yevgeniya E., Russell, Brenda
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031013/
https://ncbi.nlm.nih.gov/pubmed/17698065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.07.070
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