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Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells

Differences in ex vivo cell culture conditions can drastically affect stem cell physiology. We sought to establish an assay for measuring the effects of chemical, environmental, and genetic manipulations on the precision of repair at a single DNA double-strand break (DSB) in pluripotent and somatic...

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Bibliografiske detaljer
Main Authors: Fung, Hua, Weinstock, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102116/
https://ncbi.nlm.nih.gov/pubmed/21633706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020514
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