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Targeting abnormal DNA double strand break repair in cancer

A major challenge in cancer treatment is the development of therapies that target cancer cells with little or no toxicity to normal tissues and cells. Alterations in DNA double strand break (DSB) repair in cancer cells include both elevated and reduced levels of key repair proteins and changes in th...

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Detalhes bibliográficos
Main Authors: Rassool, Feyruz V., Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014093/
https://ncbi.nlm.nih.gov/pubmed/20697770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0493-5
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