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Targeting abnormal DNA double strand break repair in cancer

A major challenge in cancer treatment is the development of therapies that target cancer cells with little or no toxicity to normal tissues and cells. Alterations in DNA double strand break (DSB) repair in cancer cells include both elevated and reduced levels of key repair proteins and changes in th...

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Bibliografiske detaljer
Main Authors: Rassool, Feyruz V., Tomkinson, Alan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014093/
https://ncbi.nlm.nih.gov/pubmed/20697770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0493-5
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