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Tyrosine Sulfation of Native Mouse Psgl-1 Is Required for Optimal Leukocyte Rolling on P-Selectin In Vivo

BACKGROUND: We recently demonstrated that tyrosine sulfation is an important contributor to monocyte recruitment and retention in a mouse model of atherosclerosis. P-selectin glycoprotein ligand-1 (Psgl-1) is tyrosine-sulfated in mouse monocyte/macrophages and its interaction with P-selectin is impo...

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Autori principali: Westmuckett, Andrew D., Thacker, Kelly M., Moore, Kevin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102115/
https://ncbi.nlm.nih.gov/pubmed/21633705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020406
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