Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

P-selectin glycoprotein ligand 1 (PSGL-1) is a mucin-like selectin counterreceptor that binds to P-selectin, E-selectin, and L-selectin. To determine its physiological role in cell adhesion as a mediator of leukocyte rolling and migration during inflammation, we prepared mice genetically deficient i...

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Bibliographic Details
Main Authors: Yang, Jing, Hirata, Takako, Croce, Kevin, Merrill-Skoloff, Glenn, Tchernychev, Boris, Williams, Eric, Flaumenhaft, Robert, Furie, Barbara C., Furie, Bruce
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195714/
https://ncbi.nlm.nih.gov/pubmed/10601352
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