Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow

In inflamed venules, leukocytes use P-selectin glycoprotein ligand-1 (PSGL-1) to roll on P-selectin and E-selectin and to activate integrin αLβ2 (lymphocyte function-associated antigen-1, LFA-1) to slow rolling on intercellular adhesion molecule-1 (ICAM-1). Studies in cell lines have suggested that...

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Detalhes bibliográficos
Main Authors: Miner, Jonathan J., Xia, Lijun, Yago, Tadayuki, Kappelmayer, János, Liu, Zhenghui, Klopocki, Arkadiusz G., Shao, Bojing, McDaniel, J. Michael, Setiadi, Hendra, Schmidtke, David W., McEver, Rodger P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518905/
https://ncbi.nlm.nih.gov/pubmed/18550846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-149468
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