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Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow
In inflamed venules, leukocytes use P-selectin glycoprotein ligand-1 (PSGL-1) to roll on P-selectin and E-selectin and to activate integrin αLβ2 (lymphocyte function-associated antigen-1, LFA-1) to slow rolling on intercellular adhesion molecule-1 (ICAM-1). Studies in cell lines have suggested that...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society of Hematology
2008
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518905/ https://ncbi.nlm.nih.gov/pubmed/18550846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-149468 |
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