Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

Ischemic brain injury is a major problem associated with stroke. It has been increasingly recognized that acid-sensing ion channels (ASICs) contribute significantly to ischemic neuronal damage, but the underlying mechanism has remained elusive. Here, we show that extracellular spermine, one of the e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Duan, Bo, Wang, Yi-Zhi, Yang, Tao, Chu, Xiang-Ping, Yu, Ye, Huang, Yu, Cao, Hui, Hansen, Jillian, Simon, Roger P., Zhu, Michael X., Xiong, Zhi-Gang, Xu, Tian-Le
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101878/
https://ncbi.nlm.nih.gov/pubmed/21307247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4351-10.2011
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge