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The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-β Signaling in Breast Cancer Malignancy
Accumulating evidence indicates a functional crosstalk between the HER2 (ErbB2) tyrosine kinase and the TGF-β signaling mediated by its serine/threonine kinase receptors. In HER2-overexpressing breast cancer, this crosstalk results in increased cancer cell proliferation, survival and invasion, accel...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Hindawi Publishing Corporation
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101605/ https://ncbi.nlm.nih.gov/pubmed/21637380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/804236 |
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