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The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-β Signaling in Breast Cancer Malignancy

Accumulating evidence indicates a functional crosstalk between the HER2 (ErbB2) tyrosine kinase and the TGF-β signaling mediated by its serine/threonine kinase receptors. In HER2-overexpressing breast cancer, this crosstalk results in increased cancer cell proliferation, survival and invasion, accel...

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Detalhes bibliográficos
Autor principal: Wang, Shizhen Emily
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101605/
https://ncbi.nlm.nih.gov/pubmed/21637380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/804236
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