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Crosstalk between p53 and TGF-β Signalling
Wild-type p53 and TGF-β are key tumour suppressors which regulate an array of cellular responses. TGF-β signals in part via the Smad signal transduction pathway. Wild-type p53 and Smads physically interact and coordinately induce transcription of a number of key tumour suppressive genes. Conversely...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Hindawi Publishing Corporation
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321553/ https://ncbi.nlm.nih.gov/pubmed/22545213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/294097 |
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