Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

Von Hippel-Lindau (VHL) tumor suppressor gene mutations predispose carriers to kidney cancer. The protein pVHL has been shown to interact with microtubules (MTs), which is critical to cilia maintenance and mitotic spindle orientation. However, the function for pVHL in the regulation of MT dynamics i...

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Bibliografiska uppgifter
Huvudupphovsmän: Thoma, Claudio R., Matov, Alexandre, Gutbrodt, Katrin L., Hoerner, Christian R., Smole, Zlatko, Krek, Wilhelm, Danuser, Gaudenz
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2010
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101603/
https://ncbi.nlm.nih.gov/pubmed/20855504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006059
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