Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

Von Hippel-Lindau (VHL) tumor suppressor gene mutations predispose carriers to kidney cancer. The protein pVHL has been shown to interact with microtubules (MTs), which is critical to cilia maintenance and mitotic spindle orientation. However, the function for pVHL in the regulation of MT dynamics i...

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Autores principales: Thoma, Claudio R., Matov, Alexandre, Gutbrodt, Katrin L., Hoerner, Christian R., Smole, Zlatko, Krek, Wilhelm, Danuser, Gaudenz
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101603/
https://ncbi.nlm.nih.gov/pubmed/20855504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006059
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