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Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
Von Hippel-Lindau (VHL) tumor suppressor gene mutations predispose carriers to kidney cancer. The protein pVHL has been shown to interact with microtubules (MTs), which is critical to cilia maintenance and mitotic spindle orientation. However, the function for pVHL in the regulation of MT dynamics i...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101603/ https://ncbi.nlm.nih.gov/pubmed/20855504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006059 |
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