Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

Von Hippel-Lindau (VHL) tumor suppressor gene mutations predispose carriers to kidney cancer. The protein pVHL has been shown to interact with microtubules (MTs), which is critical to cilia maintenance and mitotic spindle orientation. However, the function for pVHL in the regulation of MT dynamics i...

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Main Authors: Thoma, Claudio R., Matov, Alexandre, Gutbrodt, Katrin L., Hoerner, Christian R., Smole, Zlatko, Krek, Wilhelm, Danuser, Gaudenz
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2010
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101603/
https://ncbi.nlm.nih.gov/pubmed/20855504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006059
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