Chargement en cours...

Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance

The indigenous methyltransferase RlmN modifies A2503 in 23S rRNA. A recently described rlmN mutation in a clinical Staphylococcus aureus isolate decreases susceptibility to linezolid and was thought to increase the extent of A2503 modification. However, we show that the mutation in fact abolishes Rl...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: LaMarre, Jacqueline M., Howden, Benjamin P., Mankin, Alexander S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101465/
https://ncbi.nlm.nih.gov/pubmed/21444696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00183-11
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!