Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI.
We established a mouse Ltk- cell line that contains within its genome a herpes simplex virus thymidine kinase gene (tk) that had been disrupted by the insertion of the recognition sequence for yeast endonuclease I-SceI. The artificially introduced 18 bp I-SceI recognition sequence was likely a uniqu...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1994
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7838718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.25.5649 |
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