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The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell–ECM signaling

The serine/threonine kinase Par1b promotes cell–cell adhesion and determines the polarity of the luminal domain in epithelial cells. In this study, we demonstrate that Par1b also regulates cell–extracellular matrix (ECM) signaling in kidney-derived Madin–Darby canine kidney (MDCK) cells and identifi...

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Bibliografiske detaljer
Main Authors: Cohen, David, Fernandez, Dawn, Lázaro-Diéguez, Francisco, Müsch, Anne
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101094/
https://ncbi.nlm.nih.gov/pubmed/21282462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007002
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