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The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell–ECM signaling

The serine/threonine kinase Par1b promotes cell–cell adhesion and determines the polarity of the luminal domain in epithelial cells. In this study, we demonstrate that Par1b also regulates cell–extracellular matrix (ECM) signaling in kidney-derived Madin–Darby canine kidney (MDCK) cells and identifi...

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Autors principals: Cohen, David, Fernandez, Dawn, Lázaro-Diéguez, Francisco, Müsch, Anne
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101094/
https://ncbi.nlm.nih.gov/pubmed/21282462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007002
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