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The PAR-1 serine/threonine kinase regulates epithelial detachment and directional protrusion of migrating border cells

BACKGROUND: Many cells that migrate during normal embryonic development or in metastatic cancer first detach from an epithelium. However, this step is often difficult to observe directly in vivo and the mechanisms controlling the ability of cells to leave the epithelium are poorly understood. In add...

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Bibliographic Details
Main Authors: McDonald, Jocelyn A., Khodyakova, Anna, Aranjuez, George, Dudley, Colleen, Montell, Denise J.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593744/
https://ncbi.nlm.nih.gov/pubmed/18976916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.09.041
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