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Doxycycline Ameliorates the Susceptibility to Aortic Lesions in a Mouse Model for the Vascular Type of Ehlers-Danlos Syndrome

The vascular form of Ehlers-Danlos syndrome (vEDS), a rare disease with grave complications resulting from rupture of major arteries, is caused by mutations of collagen type III [α1 chain of collagen type III (COL3A1)]. The only, recently proven, preventive strategy consists of the reduction of arte...

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Autors principals: Briest, Wilfried, Cooper, Timothy K., Tae, Hyun-Jin, Krawczyk, Melissa, McDonnell, Nazli B., Talan, Mark I.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101011/
https://ncbi.nlm.nih.gov/pubmed/21363928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.177782
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