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The Haploinsufficient Col3a1 Mouse as a Model for Vascular Ehlers-Danlos Syndrome

Vascular Ehlers-Danlos syndrome is a rare genetic disorder resulting from mutations in the α-1 chain of type III collagen (COL3A1) and manifesting as tissue fragility with spontaneous rupture of the bowel, gravid uterus, or large or medium arteries. The heterozygous Col3a1 knockout mouse was investi...

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Bibliografske podrobnosti
Main Authors: Cooper, T. K., Zhong, Q., Krawczyk, M., Tae, H-J., Müller, G. A., Schubert, R., Myers, L. A., Dietz, H. C., Talan, M. I., Briest, W.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970629/
https://ncbi.nlm.nih.gov/pubmed/20587693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300985810374842
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