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The Haploinsufficient Col3a1 Mouse as a Model for Vascular Ehlers-Danlos Syndrome
Vascular Ehlers-Danlos syndrome is a rare genetic disorder resulting from mutations in the α-1 chain of type III collagen (COL3A1) and manifesting as tissue fragility with spontaneous rupture of the bowel, gravid uterus, or large or medium arteries. The heterozygous Col3a1 knockout mouse was investi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970629/ https://ncbi.nlm.nih.gov/pubmed/20587693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300985810374842 |
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