Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that targets the corticostriatal system and results in progressive deterioration of cognitive, emotional, and motor skills. Although cortical and striatal neurons are widely studied in animal models of HD, there is li...

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Hlavní autoři: Miller, Benjamin R., Walker, Adam G., Barton, Scott J., Rebec, George V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2011
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100808/
https://ncbi.nlm.nih.gov/pubmed/21629717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2011.00026
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