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Understanding PLZF: Two transcriptional targets, REDD1 and smooth muscle α-actin, define new questions in growth control, senescence, self-renewal and tumor suppression
PLZF can function as a transcriptional activator or as a transcriptional repressor. Recent studies have identified two direct transcriptional targets of PLZF, REDD1 and smooth muscle α-actin. REDD1 is activated by PLZF. It mediates the PLZF-dependent downregulation of TORC1 and is responsible for th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100790/ https://ncbi.nlm.nih.gov/pubmed/21311223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.5.14829 |
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