IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation

The development and quality of a humoral immune response are largely influenced by the environment that supports the activation of naïve B cells. Human PDCs, through their unique capacity to produce high levels of IFN-α, have been shown earlier to enhance B cell responses stimulated by selected TLR...

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Autori principali: Gujer, Cornelia, Sandgren, Kerrie J., Douagi, Iyadh, Adams, William C., Sundling, Christopher, Smed-Sörensen, Anna, Seder, Robert A., Hedestam, Gunilla B. Karlsson, Loré, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2011
Soggetti:
Spotlight on Leading Edge Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100762/
https://ncbi.nlm.nih.gov/pubmed/21233412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0810460
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